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공공누리This item is licensed Korea Open Government License

Title
A mass spectrometry-based multiplex SNP genotyping by utilizing allelespecific ligation and strand displacement amplification
Author(s)
박정훈박현규신인경장효원정예림정윤경조대연
Publication Year
2017-05-15
Abstract
We herein describe a new mass spectrometry-based method for multiplex SNP genotyping by utilizing allelespecific ligation and strand displacement amplification (SDA) reaction. In this method, allele-specific ligation is first performed to discriminate base sequence variations at the SNP site within the PCR-amplified target DNA. The primary ligation probe is extended by a universal primer annealing site while the secondary 
Keyword
SNP genotyping; BRCA gene; Allele-specific ligation; Strand displacement amplification; Label-free biosensor
Journal Title
Biosensors and Bioelectronics
Citation Volume
91
ISSN
0956-5663
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Appears in Collections:
7. KISTI 연구성과 > 학술지 발표논문
URI
https://repository.kisti.re.kr/handle/10580/14716
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