download0 view120
twitter facebook

공공누리This item is licensed Korea Open Government License

Title
Silver-Loaded Biomimetic Hydroxyapatite Grafted Poly(caprolactone) Composite Nanofibers
Author(s)
R.Nirmala정인수
Publication Year
2012-02-29
Abstract
Wereportonpoly(caprolactone)(PCL)containingbiomimetichydroxyapatite(HA)and
hydroxyapatite-silver(HA-Ag)compositenanofiberspreparedviaanelectrospinningprocessforthebiomedicalapplications.Themorphology,structureandthermalpropertiesofthePCL,PCL/HAandPCL/HA-Agcompositenanofiberswerecharacterizedbyscanningelectronmicroscopy(SEM),transmissionelectronmicroscopy(TEM),energydispersiveX-ray(EDX)spectroscopy,X-raydiffraction
(XRD)andthermogravimetry(TGA).SEMimagesrevealedthatthenanofiberswerewell-orientedandincorporatedtheHA-Agnanoparticleswell.Theadhesion,viabilityandproliferationpropertiesofcompositenanofibersanddifferentiationofosteoblastwerecarriedouttostudytheinvitrocellcompatibilityofthePCL/HA/HA-Agcompositenanofibers.OurresultsshowedthatpristinePCLandPCL/HAcompositenanofibersscaffoldcanbeutilizedfortheboneregenerationapplications,however,PCL/HA-Agcompositenanofibersresultsinmildcytotoxiceffecttohumancells.
Keyword
Electrospinning; PCL; BiomimeticHydroxyapatite; SilverNanoparticles; CompositeNanofibers; CellCulture; Cytotoxicity.
Journal Title
Journalofbiomedicalnanotechnology
Citation Volume
8
ISSN
1550-7033
Files in This Item:
There are no files associated with this item.
Appears in Collections:
7. KISTI 연구성과 > 학술지 발표논문
URI
https://repository.kisti.re.kr/handle/10580/14082
Export
RIS (EndNote)
XLS (Excel)
XML

Browse