We performed molecular dynamics simulations on dimyristoylphosphatidylcholine lipid bilayer with 50 mol%
halothane. The structural properties, electron density profile, segmental order parameter of acyl chains, headgroup
orientation distribution, water dipole orientation distribution, have been examined. Overall the effects of the
halothane molecules on structural properties of DMPC lipid bilayer were found to be small. The electron density
profiles, the segmental order parameter, the headgroup orientation, the water dipole orientation were not affected
significantly by the halothane molecules. Pressure tensor calculations shows that the lateral pressure increases at the
hydrocarbon tail region and the headgroup region, and decreases at the water-headgroup interfacial region.