Performance analysis and optimization of AMGA for the large-scale virtual screening

Abstract

This paper addresses performance issues on ARDA Metadata Grid Application (AMGA) and presents new techniques to improve the throughput of AMGA for the WISDOM environment. The first issue is a performance degradation problem when AMGA is used as a metadata service for task retrieval in the WISDOM environment. To deal with the issue, a new AMGA operation designed to reduce the communication overhead required to retrieve a task from AMGA is proposed. According to a performance study conducted ...