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공공누리This item is licensed Korea Open Government License

Title
Comparative Study of the Prion Proteins Isolated from Reptile, Rodent, Ruminant, and Human Species using Bioinformatics Techniques
Author(s)
안인성손현석
Publication Year
2007-12-31
Abstract
In the present study, phylogram for each PrP sequence was generated by PAUP* 4.0 program using Neighbor-Joining method with 1,000 times bootstrapping process for the phylogenetic analysis. The molecular dynamics (MD) simulations were performed by the SANDER module in the AMBER 7 package using Amber 99 force field. All the simulation process was conducted in the IBM p690 Supercomputing System in Korea Institute of Science and Technology Information. To reduce the calculation time, we used ‘the Generalized Born (GB) model’.
Keyword
computational biology; neurodegenerative diseases; phylogeny; prions; proteomics
Journal Title
Experimental & molecular medicine
Citation Volume
39
ISSN
1226-3613
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Appears in Collections:
7. KISTI 연구성과 > 학술지 발표논문
URI
https://repository.kisti.re.kr/handle/10580/13655
http://www.ndsl.kr/ndsl/search/detail/article/articleSearchResultDetail.do?cn=NART37591633
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